dentate nucleus การใช้

• The dentate nucleus is not affected until late in disease progression.
• Abnormalities are seen in the basal ganglia and dentate nucleus.
• Similar abnormalities have been identified in the brainstem and cerebellar dentate nucleus.
• The dentate nucleus is mostly responsible for planning and execution of fine movement.
• Dentate nucleus axons can be divergent or convergent.
• The dentate nucleus is responsible for the planning, initiation and control of voluntary movements.
• The dentate nucleus sends commands and information to the motor and premotor areas in the forebrain.
• Morphological changes in the dentate nucleus may contribute to the pathological substrate of myoclonus in AD.
• Bilaterally symmetric defects are seen in the periaqueductal grey matter, brain stem, basal ganglia, and dentate nucleus.
• Three modalities are received by cerebellum, including proprioception, nociception, and somatic input, and all of these stimulate the dentate nucleus.
• While the primary role of the dentate nucleus is control of the movement, it does play a role in sensory processing as well.
• Since any motor function requires sensory information, it can be assumed that the dentate nucleus receives and modulates this sensory information, though the specific mechanism of this remains unclear.
• The bereitschaftspotential has also been found to be influenced by movement disorders such as Parkinson s disease ( PD ), cerebellar lesions, and degenerative diseases of the dentate nucleus.
• The lesion of the dentate nucleus consists of progressive and selective atrophy of large glutamatergic neurons and grumose degeneration of corticonuclear synaptic terminals that contain gamma-aminobutyric acid ( GABA ).
• The interpositus nucleus is involved with motor function, the dentate nucleus with cognitive functions, and the fastigial nucleus with limbic functions . supporting the view that the dentate nucleus is responsible for cognitive functions.
• The interpositus nucleus is involved with motor function, the dentate nucleus with cognitive functions, and the fastigial nucleus with limbic functions . supporting the view that the dentate nucleus is responsible for cognitive functions.
• During 22-28 weeks of gestation, which is the critical period in fetal development of the dentate nucleus, gyral formation occurs extensively over the entire surface . and the most frequent neuronal types are medium sized to large neurons.
• "' Langerhans cell histiocytosis ( LCH ) "': LCH is an aggressive disorder due to proliferation of Langerhans cell hystiocytes, and the dentate nucleus is believed to be involved in up to 40 percent of patients.
• Many studies suggested that lesions of the dentate nucleus produced an apparent reduction of symptoms, however the success of these studies did not attain the same level of success that was found when using the method to treat Parkinson s disease.
• Although no point-to-point connectivity has been observed between the dentate nucleus and the thalamus, it is believed that there is a pre-wired connectivity between a single dentate site and several body part representations in the thalamus.